Natural progesterone cream is a topically applied cream that contains the female hormone progesterone, which is normally manufactured by the corpus luteum inside the body. During a normal menstrual cycle, women produce from 20 mg to 30 mg of progesterone on a daily basis when in the luteal phase.
Progesterone is required for women to retain their health. However, after menopause, levels of the hormone can drop by 40 percent to 100 percent in some women. This has created a need for hormone replacement therapy. Unfortunately, the therapy pushed on to doctors by the pharmaceutical companies has involved synthetic hormones. Later, doctors discovered that a cream made with natural progesterone works just as well or, in many cases, better than the ingested synthetic hormones.
Benefits of Natural Progesterone Cream
When women do not naturally produce enough progesterone, it can lead to a condition that has been termed estrogen dominance. Estrogen dominance occurs most often in postmenopausal women, but it can also occur in premenopausal women who either overproduce estrogen or under-produce progesterone. The condition is characterized as a hormonal imbalance that occurs when women have too much estrogen in their system in comparison to progesterone. Some of the symptoms that can occur due to estrogen dominance include the following:
- Increase in body fat
- Weight gain
- Depression
- Increased anxiety
- Headache
- Increased risk of breast cancer
The use of naturally-derived progesterone cream can prevent these symptoms from occurring and can alleviate them if they have already begun. In some cases, this cream can also benefit women who suffer from the standard symptoms of premenstrual syndrome (PMS). Other benefits of the cream that have been reported are as follows:
- Improvement in skin tone
- Improvement of skin conditions, including acne, psoriasis, rosacea and seborrhea
- Improved sleeping pattern
- Diminished muscle aches
- Improved memory and brain function
Natural Progesterone Cream Uses
Progesterone is a fat-soluble hormone that is easily absorbed into the fatty tissues of the body through the skin. Once it gets into the subcutaneous fat, it is absorbed by the capillaries that come into contact with the fat and into the bloodstream.
The recommended dose of natural progesterone is 15 mg to 24 mg each day for the 14 days before menses in premenopausal women. For postmenopausal women, the average dose is about 15 mg per day for 25 days each month. For a cream with 450 mg to 500 mg progesterone per ounce, one-quarter teaspoon is equal to 20 mg progesterone.
The cream is safe to be used anywhere on the body, including the face, but for quicker and more efficient absorption, it is recommended to use it where capillaries are near the skin, such as on the neck, chest, breasts, palms, face and inner arms.
Natural Progesterone Cream Side Effects
When used at the recommended doses, natural progesterone has absolutely zero side effects. While ingested synthetic progesterone, known as progestin, can cause side effects and an increase in birth defects, this is not the case with topically applied cream containing natural progesterone.
Bioidentical Progesterone Cream
Bioidentical types of progesterone cream are recommended for use. These creams contain progesterone that is made up of smaller molecules that are more readily absorbed by the skin into the fatty tissues. Bioidentical progesterone can be purchased in the United States without a prescription, unlike progestin. The natural, bioidentical progesterone sold today has been used successfully by women for over 30 years, has no side effects when used correctly and is only half the cost of synthetic progestin.
Top Brands
Cream with natural progesterone has been manufactured in the United States by compounding pharmacists for decades. Some of the leading companies and brands are as follows (not in any particular order):
- Bio-Nutritional Formulas – Fem-Gest
- Broadmoore Labs – Natra-Gest
- Dr. Randolph’s Natural Balance Cream
- Easy Way International – Gentle Changes
- Emerita – Pro-Gest
- The Health and Science Research Institute – Serenity
- Kevala – PureGest
- Nature’s Sunshine – Pro-G-Yam
- Products of Nature – Natural Woman
- Pure Essence Labs – FemCreme
- Springboard – ProBalance
- Vitamin Research Products – HerBalance
- Source Naturals – Natural Progesterone Cream
Dr. John Lee’s List of Natural Progesterone Creams


